Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
GGH Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
13264-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GGH Fusion Protein Ag3939 (23-318 aa encoded by BC025025)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LSRPHGDTA KKPIIGILMQ KCRNKVMKNY GRYYIAASYV KYLESAGARV VPVRLDLTEK DYEILFKSIN GILFPGGSVD LRRSDYAKVA KIFYNLSIQS FDDGDYFPVW GTCLGFEELS LLISGECLLT ATDTVDVAMP LNFTGGQLHS RMFQNFPTEL LLSLAVEPLT ANFHKWSLSV KNFTMNEKLK KFFNVLTTNT DGKIEFISTM EGYKYPVYGV QWHPEKAPYE WKNLDGISHA PNAVKTAFYL AEFFVNEARK NNHHFKSESE EEKALIYQFS PIYTGNISSF QQCYIFD (23-318 aa encoded by BC025025)
Target Information
Gamma-Glutamyl hydrolase (GGH) is a homodimeric protein that catalyzes the cleavage of the gamma-glutamyl chain of folylpoly-gamma-glutamyl substrates and is a central enzyme in folyl and antifolyl poly-gamma-glutamate metabolism. The activities of the baculovirus-expressed enzyme and the enzyme from HL-60 cells were similar on methotrexate polyglutamates. GGH is expressed in a variety of human tumors and correlates with poor prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Conjugase; FGPH; Folylpolyglutamate hydrolase; Gamma-Glu-X carboxypeptidase; Gamma-glutamyl hydrolase; gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase); GH
Gene Aliases: gamma-GH; GGH; GH
UniProt ID: (Human) Q92820, (Mouse) Q9Z0L8, (Rat) Q62867
Entrez Gene ID: (Human) 8836, (Mouse) 14590, (Rat) 25455
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support