Product References
Prolonged dysbiosis and altered immunity under nutritional intervention in a physiological mouse model of severe acute malnutrition.
iScience
Hidalgo-Villeda F,Million M,Defoort C,Vannier T,Svilar L,Lagier M,Wagner C,Arroyo-Portilla C,Chasson L,Luciani C,Bossi V,Gorvel JP,Lelouard H,Tomas J
50-5902-82 was used in Flow cytometry/Cell sorting to provide a preclinical model of SAM and have identified key markers to target with future interventions during the education of the immune system to improve SAM whole defects.
Fri Jun 16 00:00:00 UTC 2023
Continuous germinal center invasion contributes to the diversity of the immune response.
Cell
Hägglöf T,Cipolla M,Loewe M,Chen ST,Mesin L,Hartweger H,ElTanbouly MA,Cho A,Gazumyan A,Ramos V,Stamatatos L,Oliveira TY,Nussenzweig MC,Viant C
50-5902-82 was used in Flow cytometry/Cell sorting to show that naive B cells continuously enter GCs where they compete for T cell help and undergo clonal expansion.
Thu Jan 05 00:00:00 UTC 2023
An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo.
Cancer letters
Xing Y,Guo W,Wu M,Xie J,Huang D,Hu P,Zhou M,Zhang L,Zhang Q,Wang P,Wang X,Wang G,Wu H,Zhou C,Chen Y,Liu M,Yi Z,Sun Z
50-5902-82 was used in Flow Cytometry to identify and test WK500B as a promising candidate that could be developed as an effective orally available therapeutic agent for diffuse large B cell lymphoma.
Thu Mar 31 00:00:00 UTC 2022
Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells.
Cell
Omer-Javed A,Pedrazzani G,Albano L,Ghaus S,Latroche C,Manzi M,Ferrari S,Fiumara M,Jacob A,Vavassori V,Nonis A,Canarutto D,Naldini L
50-5902-82 was used in flow cytometry to provide a potentially valuable strategy paving the way to broader and safer use of HSPC-GT.
Thu Jun 23 00:00:00 UTC 2022
Sequencing, cloning, and antigen binding analysis of monoclonal antibodies isolated from single mouse B cells.
STAR protocols
Viant C,Escolano A,Chen ST,Nussenzweig MC
50-5902-82 was used in Flow Cytometry to analyze the BCRs of different mouse B cell populations for somatic hypermutations, clonal and phylogenic relationships, and their affinity for cognate antigen.
Fri Jun 18 00:00:00 UTC 2021
Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.
Cell metabolism
Rosser EC,Piper CJM,Matei DE,Blair PA,Rendeiro AF,Orford M,Alber DG,Krausgruber T,Catalan D,Klein N,Manson JJ,Drozdov I,Bock C,Wedderburn LR,Eaton S,Mauri C
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Immunohistochemistry
Tue Apr 07 00:00:00 UTC 2020
The B-cell antigen receptor of IgE-switched plasma cells regulates memory IgE responses.
The Journal of allergy and clinical immunology
Schmitt MER,Lutz J,Haase P,Bösl MR,Wienands J,Engels N,Voehringer D
50-5902-82 was used in Flow Cytometry to aim at clarifying whether inactivation of the cytoplasmic immunoglobulin tail tyrosine (ITT) motif in transmembrane IgE (mIgE) impairs the memory IgE response in mice.
Tue Sep 01 00:00:00 UTC 2020
KSHV LANA acetylation-selective acidic domain reader sequence mediates virus persistence.
Proceedings of the National Academy of Sciences of the United States of America
Juillard F,de Miranda MP,Li S,Franco A,Seixas AF,Liu B,Álvarez ÁL,Tan M,Szymula A,Kaye KM,Simas JP
50-5902 was used in Flow cytometry/Cell sorting to implicate an acetylation-dependent mechanism mediating KSHV persistence and expand the role of acidic domain readers.
Tue Sep 08 00:00:00 UTC 2020
Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity.
Nature communications
Kimura S,Nakamura Y,Kobayashi N,Shiroguchi K,Kawakami E,Mutoh M,Takahashi-Iwanaga H,Yamada T,Hisamoto M,Nakamura M,Udagawa N,Sato S,Kaisho T,Iwanaga T,Hase K
50-5902 was used in Flow cytometry/Cell sorting to identify that the balance between infectious risk and the ability to perform immunosurveillance at the mucosal surface is dependent on osteprotegerin-dependent self-regulation of M cell differentiation.
Mon Jan 13 00:00:00 UTC 2020
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Mon Jun 03 00:00:00 UTC 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Mon Jun 03 00:00:00 UTC 2019
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Mon Jun 03 00:00:00 UTC 2019
αv Integrins regulate germinal center B cell responses through noncanonical autophagy.
The Journal of clinical investigation
Raso F,Sagadiev S,Du S,Gage E,Arkatkar T,Metzler G,Stuart LM,Orr MT,Rawlings DJ,Jackson SW,Lacy-Hulbert A,Acharya M
50-5902 was used in Flow cytometry/Cell sorting to identify a mechanism of regulation of germinal centre B cell TLR signalling, mediated by αv integrins and noncanonical autophagy.
Fri Aug 31 00:00:00 UTC 2018
In Vivo Persistence of Chimeric Virus after Substitution of the Kaposi's Sarcoma-Associated Herpesvirus LANA DNA Binding Domain with That of Murid Herpesvirus 4.
Journal of virology
Pires de Miranda M,Quendera AP,McVey CE,Kaye KM,Simas JP
50-5902 was used in Flow cytometry/Cell sorting to report a recombinant, chimeric MuHV-4 which contains kLANA in place of mLANA, but in which the DBD is replaced with that of mLANA.
Thu Nov 01 00:00:00 UTC 2018
Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice.
Molecular medicine reports
Wang X,Zhang Y,Wang Z,Liu X,Zhu G,Han G,Chen G,Hou C,Wang T,Shen B,Li Y,Xiao H,Ma N,Wang R
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Mon Jan 01 00:00:00 UTC 2018
Act1 is a negative regulator in T and B cells via direct inhibition of STAT3.
Nature communications
Zhang CJ,Wang C,Jiang M,Gu C,Xiao J,Chen X,Martin BN,Tang F,Yamamoto E,Xian Y,Wang H,Li F,Sartor RB,Smith H,Husni ME,Shi FD,Gao J,Carman J,Dongre A,McKarns SC,Coppieters K,Jørgensen TN,Leonard WJ,Li X
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Mon Jul 16 00:00:00 UTC 2018
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus.
Nature communications
Liu J,Huang X,Hao S,Wang Y,Liu M,Xu J,Zhang X,Yu T,Gan S,Dai D,Luo X,Lu Q,Mao C,Zhang Y,Shen N,Li B,Huang M,Zhu X,Jin J,Cheng X,Sun SC,Xiao Y
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Mon Mar 19 00:00:00 UTC 2018
B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.
Nature communications
Barwick BG,Scharer CD,Martinez RJ,Price MJ,Wein AN,Haines RR,Bally APR,Kohlmeier JE,Boss JM
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Immunofluorescence
Tue May 15 00:00:00 UTC 2018
T-Bet+ IgM Memory Cells Generate Multi-lineage Effector B Cells.
Cell reports
Kenderes KJ,Levack RC,Papillion AM,Cabrera-Martinez B,Dishaw LM,Winslow GM
50-5902 was used in Flow cytometry/Cell sorting to propose that T-bet+ IgM memory cells can differentiate into any effector B cell lineage to provide long-term multifunctional immunity.
Tue Jul 24 00:00:00 UTC 2018
EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production.
Journal of immunology (Baltimore, Md. : 1950)
Guo M,Price MJ,Patterson DG,Barwick BG,Haines RR,Kania AK,Bradley JE,Randall TD,Boss JM,Scharer CD
50-5902-82 was used in Flow Cytometry to demonstrate that EZH2 is essential in facilitating epigenetic changes that regulate ASC fate, function, and metabolism.
Thu Feb 01 00:00:00 UTC 2018
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.
Cell metabolism
Westerterp M,Gautier EL,Ganda A,Molusky MM,Wang W,Fotakis P,Wang N,Randolph GJ,D'Agati VD,Yvan-Charvet L,Tall AR
50-5902 was used in Flow cytometry/Cell sorting to identify an essential role of DC cholesterol efflux pathways in maintaining immune tolerance.
Tue Jun 06 00:00:00 UTC 2017
Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin.
Frontiers in immunology
Sun JB,Holmgren J,Larena M,Terrinoni M,Fang Y,Bresnick AR,Xiang Z
Wed Nov 20 00:00:00 UTC 2019
Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin.
Frontiers in immunology
Sun JB,Holmgren J,Larena M,Terrinoni M,Fang Y,Bresnick AR,Xiang Z
Wed Nov 20 00:00:00 UTC 2019
Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin.
Frontiers in immunology
Sun JB,Holmgren J,Larena M,Terrinoni M,Fang Y,Bresnick AR,Xiang Z
Wed Nov 20 00:00:00 UTC 2019
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Tue Oct 17 00:00:00 UTC 2017
Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development.
The Journal of experimental medicine
Wöhner M,Tagoh H,Bilic I,Jaritz M,Poliakova DK,Fischer M,Busslinger M
50-5902 was used in Immunohistochemistry to identify E2A and E2-2 as central regulators of B cell immunity.
Mon Jun 27 00:00:00 UTC 2016
NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.
The Journal of experimental medicine
de Valle E,Grigoriadis G,O'Reilly LA,Willis SN,Maxwell MJ,Corcoran LM,Tsantikos E,Cornish JK,Fairfax KA,Vasanthakumar A,Febbraio MA,Hibbs ML,Pellegrini M,Banerjee A,Hodgkin PD,Kallies A,Mackay F,Strasser A,Gerondakis S,Gugasyan R
50-5902 was used in Flow cytometry/Cell sorting to identify a novel role of NFκB1 in preventing multiorgan autoimmunity through the negative regulation of Il-6 gene expression in follicular B cells.
Mon Apr 04 00:00:00 UTC 2016
CD4 T Helper Cells Instruct Lymphopenia-Induced Memory-Like CD8 T Cells for Control of Acute LCMV Infection.
Frontiers in immunology
Schmitt ME,Sitte S,Voehringer D
50-5902 was used in Flow cytometry/Cell sorting to determine whether memory-like T cells can efficiently respond to foreign antigen and participate in antiviral immunity.
Wed Nov 20 00:00:00 UTC 2019
Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis.
Arthritis research & therapy
Andersson SE,Eneljung T,Tengvall S,Jirholt P,Stern A,Henningsson L,Liang B,Thorarinsdottir K,Kihlberg J,Holmdahl R,Mårtensson IL,Gustafsson K,Gjertsson I
50-5902 was used in Immunofluorescence to investigate how endogenous presentation of the CII-peptide on B cells is one of the key contributors to arthritis tolerance induction and maintenance.
Tue Jun 14 00:00:00 UTC 2016
Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection.
Journal of immunology (Baltimore, Md. : 1950)
Hilpert C,Sitte S,Matthies A,Voehringer D
50-5902 was used in Flow cytometry/Cell sorting to study the role of dendritic cells as antigen presenting cells and a source of type I interferons in acute lymphocytic choriomeningitis virus infection.
Sat Oct 01 00:00:00 UTC 2016
Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization.
Nature communications
Bemark M,Hazanov H,Strömberg A,Komban R,Holmqvist J,Köster S,Mattsson J,Sikora P,Mehr R,Lycke NY
50-5902 was used in Immunohistochemistry to study the effects of oral immunisation on inducing gut mucosal memory in B cells.
Tue Sep 06 00:00:00 UTC 2016
Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization.
Nature communications
Bemark M,Hazanov H,Strömberg A,Komban R,Holmqvist J,Köster S,Mattsson J,Sikora P,Mehr R,Lycke NY
50-5902 was used in Immunohistochemistry to study the effects of oral immunisation on inducing gut mucosal memory in B cells.
Tue Sep 06 00:00:00 UTC 2016
Interleukin 21 signaling in B cells is required for efficient establishment of murine gammaherpesvirus latency.
PLoS pathogens
Collins CM,Speck SH
50-5902 was used in Flow cytometry/Cell sorting to identify IL-21 as an important T follicular helper (TFH) cell-derived factor needed for establishment of murine gammaherpesvirus latency.
Wed Apr 01 00:00:00 UTC 2015
Gammaherpesvirus Co-infection with Malaria Suppresses Anti-parasitic Humoral Immunity.
PLoS pathogens
Matar CG,Anthony NR,O'Flaherty BM,Jacobs NT,Priyamvada L,Engwerda CR,Speck SH,Lamb TJ
50-5902 was used in Immunofluorescence to demonstrate that an acute gammaherpesvirus infection can negatively impact the development of an anti-malarial immune response.
Fri May 01 00:00:00 UTC 2015
BILL-cadherin/cadherin-17 contributes to the survival of memory B cells.
PloS one
Funakoshi S,Shimizu T,Numata O,Ato M,Melchers F,Ohnishi K
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Wed Sep 16 00:00:00 UTC 2015
Mutation of POLB causes lupus in mice.
Cell reports
Senejani AG,Liu Y,Kidane D,Maher SE,Zeiss CJ,Park HJ,Kashgarian M,McNiff JM,Zelterman D,Bothwell AL,Sweasy JB
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Flow Cytometry
Thu Jan 16 00:00:00 UTC 2014
Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria.
The EMBO journal
Panda S,Zhang J,Tan NS,Ho B,Ding JL
Published figure using GL7 monoclonal antibody (Product # 50-5902-82) in Immunofluorescence
Wed Nov 13 00:00:00 UTC 2013
Human B-lymphocytes express alpha2-6-sialylated 6-sulfo-N-acetyllactosamine serving as a preferred ligand for CD22/Siglec-2.
The Journal of biological chemistry
Kimura N,Ohmori K,Miyazaki K,Izawa M,Matsuzaki Y,Yasuda Y,Takematsu H,Kozutsumi Y,Moriyama A,Kannagi R
Fri Nov 02 00:00:00 UTC 2007
