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Invitrogen
GLAST Recombinant Rabbit Monoclonal Antibody (7Y4U5)
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FIGURE: 1 / 5
GLAST Antibody (MA5-38203) in IHC (P)
Immunohistochemistry analysis of GLAST in paraffin-embedded mouse spinal cord. Samples were incubated with GLAST Monoclonal antibody (Product # MA5-38203) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-38203
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7Y4U5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human EAAT1/SLC1A3 (P43003)
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2898120
Product Specific Information
Positive Samples: U-251MG, Mouse brain, Rat brain
Immunogen sequence: GTKENMHREG KIVRVTAADA FLDLIRNMFP PNLVEACFKQ FKTNYEKRSF KVPIQANETL VGAVINNVSE AMETLTRITE ELVPVPGSVN GVNALGLVVF S
Target Information
This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EAAT-1; Excitatory amino acid transporter 1; FLJ25094; GLAST; GLAST-1; Glial glutamate transporter; Glial high affinity glutamate transporter; GluT-1; glutamate transporter; glutamate/aspartate transporter; High-affinity neuronal glutamate transporter; Sodium-dependent glutamate/aspartate transporter 1; solute carrier family 1 (glial high affinity glutamate transporter), member 3; Solute carrier family 1 member 3; solute carrier family 1, member 3
Gene Aliases: AI504299; B430115D02Rik; EA6; EAAT1; GLAST; GLAST-1; GLAST1; GLU-T; GluT-1; Gmt1; MGluT1; SLC1A3
UniProt ID: (Human) P43003, (Rat) P24942, (Mouse) P56564
Entrez Gene ID: (Human) 6507, (Rat) 29483, (Mouse) 20512
neurotransmitter uptake
positive regulation of defense response to virus by host
amino acid transmembrane transport
glutamate biosynthetic process
ion transport
chemical synaptic transmission
sensory perception of sound
response to light stimulus
gamma-aminobutyric acid biosynthetic process
response to wounding
glutamate secretion
cranial nerve development
auditory behavior
response to drug
malate-aspartate shuttle
response to antibiotic
cell morphogenesis involved in neuron differentiation
positive regulation of synaptic transmission
neuromuscular process controlling balance
L-glutamate import
D-aspartate import
L-glutamate transmembrane transport
mitophagy in response to mitochondrial depolarization
xenophagy
glutamate metabolic process
neurotransmitter transport
response to inorganic substance
L-glutamate transport
sodium ion transmembrane transport
transport
dicarboxylic acid transport
response to amino acid
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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