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Immunogen sequence: HSPHQEPTVVN QIVPLSGERR YSMPPLFHTH YVPDIVRCVP PFREIAFLEP REITLPEAKD KLSQQILELF ETCQQQISDL KKKELCRT
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 89%.
GLD2 is cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. GLD2 does not play a role in replication-dependent histone mRNA degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hGLD-2; PAP-associated domain-containing protein 4; Poly(A) RNA polymerase GLD2; Terminal nucleotidyltransferase 2; Terminal uridylyltransferase 2; TUTase 2
Gene Aliases: GLD2; PAPD4; TENT2; TUT2
UniProt ID: (Human) Q6PIY7
Entrez Gene ID: (Human) 167153
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