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Proteintech
GLDC Polyclonal Antibody
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Product Details
24827-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GLDC Fusion Protein Ag20410 (675-1020 aa encoded by BC111995)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NIDAVHLKA MVDKHKENLA AIMITYPSTN GVFEENISDV CDLIHQHGGQ VYLDGANMNA QVGICRPGDF GSDVSHLNLH KTFCIPHGGG GPGMGPIGVK KHLAPFLPNH PVISLKRNED ACPVGTVSAA PWGSSSILPI SWAYIKMMGG KGLKQATETA ILNANYMAKR LETHYRILFR GARGYVGHEF ILDTRPFKKS ANIEAVDVAK RLQDYGFHAP TMSWPVAGTL MVEPTESEDK AELDRFCDAM ISIRQEIADI EEGRIDPRVN PLKMSPHSLT CVTSSHWDRP YSREVAAFPL PFVKPENKFW PTIARIDDIY GDQHLVCTCP PMEVYESPFS EQKRASS (675-1020 aa encoded by BC111995)
Target Information
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Glycine cleavage system P protein; glycine cleavage system protein P; Glycine decarboxylase; glycine decarboxylase P-protein; Glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); Glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase [decarboxylating], mitochondrial; RP11-472F14.1
Gene Aliases: D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; HYGN1
UniProt ID: (Human) P23378, (Mouse) Q91W43
Entrez Gene ID: (Human) 2731, (Mouse) 104174
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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