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Invitrogen
GLDC Monoclonal Antibody (3D3D3)
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Product Details
MA5-49279
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3D3D3
Immunogen
E.coli-derived human Glycine decarboxylase/GLDC recombinant protein (Position: K574-S1020).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3074937
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human HCCP tissue, human 293T whole cell, human A549 whole cell, rat liver tissue, rat kidney tissue, mouse liver tissue, mouse kidney tissue. IHC: human placenta tissue, human thyroiditis tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glycine cleavage system P protein; glycine cleavage system protein P; Glycine decarboxylase; glycine decarboxylase P-protein; glycine decarboxylase, glycine cleavage system protein P); Glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); Glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; RP11-472F14.1
Gene Aliases: D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; HYGN1
UniProt ID: (Human) P23378, (Mouse) Q91W43
Entrez Gene ID: (Human) 2731, (Mouse) 104174, (Rat) 309312
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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