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Product Details
PA5-52774
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GLIPR1. Recombinant protein control fragment (Product #RP-90273).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642031
Product Specific Information
Immunogen sequence: NEDFIKDCVR IHNKFRSEVK PTASDMLYMT WDPALAQIAK AWASNCQFSH NTRLKPPHKL HPNFTSLGEN IWTGSVPIFS VSSAITNWYD EIQDYDF
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 61%.
Target Information
The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer. The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GLI pathogenesis-related 1 (glioma); Glioma pathogenesis-related protein 1; GliPR 1; Protein RTVP-1; related to testis-specific, vespid, and pathogenesis proteins 1; testes-specific vespid and pathogenesis protein 1
Gene Aliases: CRISP7; GLIPR; GLIPR1; RTVP1
UniProt ID: (Human) P48060
Entrez Gene ID: (Human) 11010
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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