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GLRA2 Antibody (PA5-90611) in WB
Western blot analysis of GLRA2 in various lysates. Samples were incubated with GLRA2 Polyclonal antibody (Product # PA5-90611) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-90611
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of human GLRA2 (NP_0020541)
Conjugate
Form
Liquid
Concentration
3.48 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806145
Product Specific Information
Immunogen sequence: RLRRRQKRQN KEEDVTRESR FNFSGYGMGH CLQVKDGTAV KATPANPLPQ PPKDGDAIKK KFVDRAKRID T; Positive Samples: Mouse spinal cord, Rat brain; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels. This receptor has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem. GlyR is a pentameric receptor comprised of alpha and beta subunits. Four alpha-subunits (GLRA1, GLRA2, GLRA3, GLRA4) and one beta-subunit (GLRB) of GlyR have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glycine receptor; glycine receptor alpha 2 subunit; Glycine receptor alpha 2 subunit (glycine receptor, neonatal); Glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-2; glycine receptor, alpha 2; glycine receptor, alpha 2 subunit; glycine receptor, alpha-2 polypeptide
Gene Aliases: GLR; GLRA2; RNNEOGLY
UniProt ID: (Human) P23416, (Rat) P22771, (Mouse) Q7TNC8
Entrez Gene ID: (Human) 2742, (Rat) 24397, (Mouse) 237213
neuropeptide signaling pathway
synapse assembly
spinal cord development
ion transmembrane transport
synaptic transmission, glycinergic
cellular response to amino acid stimulus
cellular response to zinc ion
cellular response to ethanol
chloride transmembrane transport
transport
ion transport
chloride transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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