Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
GLRX2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
13381-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GLRX2 Fusion Protein Ag4218 (16-164 aa encoded by BC028113)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RSGSAGWLD RAAGAAGAAA AAASGMESNT SSSLENLATA PVNQIQETIS DNCVVIFSKT SCSYCTMAKK LFHDMNVNYK VVELDLLEYG NQFQDALYKM TGERTVPRIF VNGTFIGGAT DTHRLHKEGK LLPLVHQCYL KKSKRKEFQ (16-164 aa encoded by BC028113)
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kD dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); glutaredoxin (thioltransferase) 2; glutaredoxin 2 (thioltransferase); Glutaredoxin-2, mitochondrial
Gene Aliases: 1700010P22Rik; AI645710; CGI-133; GLRX2; GRX2
UniProt ID: (Human) Q9NS18, (Mouse) Q923X4, (Rat) Q6AXW1
Entrez Gene ID: (Human) 51022, (Mouse) 69367, (Rat) 114022
transport
response to organic substance
response to hydrogen peroxide
cell redox homeostasis
oxidation-reduction process
aging
cellular response to superoxide
regulation of transcription, DNA-templated
glutathione metabolic process
apoptotic process
response to temperature stimulus
regulation of signal transduction
cell differentiation
DNA protection
response to redox state
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support