Product References
Chinese herbal medicine alleviates the pathogenesis of polycystic ovary syndrome by improving oxidative stress and glucose metabolism via mitochondrial Sirtuin 3 signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhang Q,Ren J,Wang F,Li M,Pan M,Zhang H,Qu F
Sun Jan 01 00:00:00 UTC 2023
Fatty Acid Induced Hypermethylation in the Slc2a4 Gene in Visceral Adipose Tissue Is Associated to Insulin-Resistance and Obesity.
International journal of molecular sciences
Britsemmer JH,Krause C,Taege N,Geißler C,Lopez-Alcantara N,Schmidtke L,Naujack AM,Wagner J,Wolter S,Mann O,Kirchner H
Wed Mar 29 00:00:00 UTC 2023
Chemical Constituents and Hypoglycemic Mechanisms of Dendrobium nobile in Treatment of Type 2 Diabetic Rats by UPLC-ESI-Q-Orbitrap, Network Pharmacology and In Vivo Experimental Verification.
Molecules (Basel, Switzerland)
Li Z,Zeng M,Geng K,Lai D,Xu Z,Zhou W
Thu Mar 16 00:00:00 UTC 2023
IDH2, a novel target of OGT, facilitates glucose uptake and cellular bioenergy production via NF-κB signaling to promote colorectal cancer progression.
Cellular oncology (Dordrecht, Netherlands)
He X,Wu N,Li R,Zhang H,Zhao Y,Nie Y,Wu J
Wed Feb 01 00:00:00 UTC 2023
Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma.
Autophagy
Yao J,Tang S,Shi C,Lin Y,Ge L,Chen Q,Ou B,Liu D,Miao Y,Xie Q,Tang X,Fei J,Yang G,Tian J,Zeng X
Sat Apr 01 00:00:00 UTC 2023
The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes.
Nature communications
Wu SA,Shen C,Wei X,Zhang X,Wang S,Chen X,Torres M,Lu Y,Lin LL,Wang HH,Hunter AH,Fang D,Sun S,Ivanova MI,Lin Y,Qi L
Tue May 30 00:00:00 UTC 2023
Perturbated glucose metabolism augments epithelial cell proinflammatory function in chronic rhinosinusitis.
The Journal of allergy and clinical immunology
Chen CL,Ma J,Lu RY,Wang YT,Zhao JF,Kang YF,Hu JJ,Wang N,Song J,Zhong J,Chen C,Wang H,Liu Z
Sat Apr 01 00:00:00 UTC 2023
Perturbated glucose metabolism augments epithelial cell proinflammatory function in chronic rhinosinusitis.
The Journal of allergy and clinical immunology
Chen CL,Ma J,Lu RY,Wang YT,Zhao JF,Kang YF,Hu JJ,Wang N,Song J,Zhong J,Chen C,Wang H,Liu Z
Sat Apr 01 00:00:00 UTC 2023
The Degree of Hydrolysis and Peptide Profile Affect the Anti-Fatigue Activities of Whey Protein Hydrolysates in Promoting Energy Metabolism in Exercise Mice.
Journal of agricultural and food chemistry
Zhao C,Gong Y,Zheng L,Zhao M
Wed Feb 15 00:00:00 UTC 2023
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
FEBS open bio
Shi H,Hao X,Sun Y,Zhang H,Zhao Y,Wang B,Lu J,Hou W,Yan Y,Yu X,Xue L,Luo X,Wang H
Thu Jun 01 00:00:00 UTC 2023
Intermittent fasting attenuates obesity-related atrial fibrillation via SIRT3-mediated insulin resistance mitigation.
Biochimica et biophysica acta. Molecular basis of disease
Zhang Y,Gao F,Gong H,Fu Y,Liu B,Qin X,Zheng Q
Sat Apr 01 00:00:00 UTC 2023
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
Journal of pineal research
Qin X,Fu Y,Fan J,Liu B,Liu P,Zhang Y,Jiang T,Zheng Q
Sat Apr 01 00:00:00 UTC 2023
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
Journal of pineal research
Qin X,Fu Y,Fan J,Liu B,Liu P,Zhang Y,Jiang T,Zheng Q
Sat Apr 01 00:00:00 UTC 2023
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Antioxidants (Basel, Switzerland)
Han S,He Z,Hu X,Li X,Zheng K,Huang Y,Xiao P,Xie Q,Ni J,Liu Q
Wed Mar 15 00:00:00 UTC 2023
Visceral adipose tissue-directed human kallistatin gene therapy improves adipose tissue remodeling and metabolic health in obese mice.
Cellular signalling
Wu Y,Jiang Y,Guo JQ,Yang ZW,Carvalho A,Qian LL,Ji JJ,Ji ZJ,Ma GS,Yao YY
Thu Jun 01 00:00:00 UTC 2023
Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism.
International journal of molecular sciences
Zhang Y,Wu F,Teng F,Guo S,Li H
Fri Jan 20 00:00:00 UTC 2023
A novel regulatory mechanism of geniposide for improving glucose homeostasis mediated by circulating RBP4.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu J,Song C,Nie C,Sun Y,Wang Y,Xue L,Fan M,Qian H,Wang L,Li Y
Sat Jan 01 00:00:00 UTC 2022
α-Pyrones with glucose uptake-stimulatory activity from the twigs of Cryptocarya wrayi.
Fitoterapia
Wang XN,Kuang XD,Wang Y,Sun P,He XR,Peng YA,Liu LH,Gu JL,Gan LS,Wang XN,Shu JC,Zhou ZW
Fri Apr 01 00:00:00 UTC 2022
DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study.
Frontiers in pharmacology
Li X,Wen H,Zhang Y,Liu A,Zhang X,Fu M,Pan Y,Xu J,Zhang J
Tue Sep 20 00:00:00 UTC 2022
Remodeling on adipocytic physiology of organophosphorus esters in mature adipocytes.
Environmental pollution (Barking, Essex : 1987)
Liu Y,Le Y,Xu M,Wang W,Chen H,Zhang Q,Wang C
Fri Jul 15 00:00:00 UTC 2022
A Metabolism-Related Gene Landscape Predicts Prostate Cancer Recurrence and Treatment Response.
Frontiers in immunology
Zhou L,Fan R,Luo Y,Zhang C,Jia D,Wang R,Zeng Y,Ren M,Du K,Pan W,Yang J,Tian F,Gu C
Fri Apr 08 00:00:00 UTC 2022
Alpha-Ketoglutarate Alleviates Neuronal Apoptosis Induced by Central Insulin Resistance through Inhibiting S6K1 Phosphorylation after Subarachnoid Hemorrhage.
Oxidative medicine and cellular longevity
Ding PF,Zhu Q,Sheng B,Yang H,Xu HJ,Tao T,Peng Z,Chen XX,Li XJ,Zhou Y,Zhang HS,Gao YY,Zhuang Z,Hang CH,Li W
Wed Sep 07 00:00:00 UTC 2022
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Frontiers in pharmacology
Ye Z,Ma J,Liu Y,Xu B,Dai X,Fu M,Tian T,Sui X,Mo F,Gao S,Zhao D,Zhang D
Wed Sep 28 00:00:00 UTC 2022
Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice.
Frontiers in pharmacology
Ye Z,Ma J,Liu Y,Xu B,Dai X,Fu M,Tian T,Sui X,Mo F,Gao S,Zhao D,Zhang D
Wed Sep 28 00:00:00 UTC 2022
Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway.
Journal of ginseng research
Ni J,Liu Z,Jiang M,Li L,Deng J,Wang X,Su J,Zhu Y,He F,Mao J,Gao X,Fan G
Tue Mar 01 00:00:00 UTC 2022
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Oxidative medicine and cellular longevity
Zhang YL,Li PB,Han X,Zhang B,Li HH
Tue May 24 00:00:00 UTC 2022
Exercise improves high-fat diet-induced metabolic disorder by promoting HDAC5 degradation through the ubiquitin-proteasome system in skeletal muscle.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
Huang S,Zheng X,Zhang X,Jin Z,Liu S,Fu L,Niu Y
Tue Nov 01 00:00:00 UTC 2022
A diarylheptanoid compound from Alpinia officinarum Hance ameliorates high glucose-induced insulin resistance by regulating PI3K/AKT-Nrf2-GSK3β signaling pathways in HepG2 cells.
Journal of ethnopharmacology
Zhang XG,Liu AX,Zhang YX,Zhou MY,Li XY,Fu MH,Pan YP,Xu J,Zhang JQ
Thu Sep 15 00:00:00 UTC 2022
Fermented noni (Morinda citrifolia L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells.
Food & function
Zhang X,Zhang B,Li L,Li X,Zhang J,Chen G
Mon Aug 01 00:00:00 UTC 2022
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Clinical and experimental pharmacology & physiology
Wang P,Li CG,Zhou X,Ding S
Tue Feb 01 00:00:00 UTC 2022
Elucidation of the interaction effect between dietary fiber and bound polyphenol components on the anti-hyperglycemic activity of tea residue dietary fiber.
Food & function
Huang H,Chen J,Hu X,Chen Y,Xie J,Ao T,Wang H,Xie J,Yu Q
Mon Mar 07 00:00:00 UTC 2022
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Genetics research
Lin L,Wang X,Zhao W,Chen Y
Mon Nov 07 00:00:00 UTC 2022
The influence of perinatal maternal exposure to dibutyl phthalate on glucolipid metabolism in adult female offspring.
Obesity research & clinical practice
Zhou K,Cheng R,Zhu M,Yang M,Shen X,Luo X,Ma L,Xu L,Zhang J
Mon Dec 12 00:00:00 UTC 2022
Effects of distinct n-6 to n-3 polyunsaturated fatty acid ratios on insulin resistant and AD-like phenotypes in high-fat diets-fed APP/PS1 mice.
Food research international (Ottawa, Ont.)
Ma X,Guo Y,Xu J,Wang X,Dong S,Gao Y,Van Halm-Lutterodt N,Yuan L
Thu Dec 01 00:00:00 UTC 2022
Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells.
Cells
Wang Y,Wang Y,Li F,Zou J,Li X,Xu M,Yu D,Ma Y,Huang W,Sun X,Zhang Y
Tue Mar 22 00:00:00 UTC 2022
Dietary Nε-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
World journal of diabetes
Wang ZQ,Sun Z
Tue Nov 15 00:00:00 UTC 2022
Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension.
International journal of molecular sciences
Kosmas K,Michael Z,Papathanasiou AE,Spyropoulos F,Adib E,Jasuja R,Christou H
Sun Sep 18 00:00:00 UTC 2022
Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro.
Frontiers in neuroscience
Yang X,Xu Y,Gao W,Wang L,Zhao X,Liu G,Fan K,Liu S,Hao H,Qu S,Dong R,Ma X,Ma J
Tue Dec 06 00:00:00 UTC 2022
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Acta diabetologica
Dai HB,Wang HY,Wang FZ,Qian P,Gao Q,Zhou H,Zhou YB
Sun May 01 00:00:00 UTC 2022
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Frontiers in endocrinology
Tao J,Yu XL,Yuan YJ,Shen X,Liu J,Gu PP,Wang Z,Ma YT,Li GQ
Fri Apr 22 00:00:00 UTC 2022
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Frontiers in endocrinology
Tao J,Yu XL,Yuan YJ,Shen X,Liu J,Gu PP,Wang Z,Ma YT,Li GQ
Fri Apr 22 00:00:00 UTC 2022
Integrated analysis of long non-coding RNAs and mRNAs associated with malignant transformation of gastrointestinal stromal tumors.
Cell death & disease
Yin X,Yin Y,Dai L,Shen C,Chen N,Li J,Cai Z,Jiang Z,Wang J,Zhao Z,Chen X,Deng H,Zhang B
Sat Jul 03 00:00:00 UTC 2021
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters.
Journal of natural medicines
Jiang MJ,Li L,Huang WF,Su J,Li YH,Qu XS,Fan LL
Wed Sep 01 00:00:00 UTC 2021
Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway.
Oxidative medicine and cellular longevity
Bai Y,Zuo J,Fang X,Ma R,Tian T,Mo F,Mu Q,Zhang Y,Yu N,Bao X,Zhang D,Gao S,Zhao D
Fri Jan 28 00:00:00 UTC 2022
Mechanism of Electroacupuncture Regulating IRS-1 Phosphorylation in Skeletal Muscle to Improve Insulin Sensitivity.
Evidence-based complementary and alternative medicine : eCAM
Song S,Li R,Cao B,Zhang J,Kim Y,Kim B,Yu X
Sun Mar 31 00:00:00 UTC 2024
Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.
Oxidative medicine and cellular longevity
Wu R,Jian T,Ding X,Lv H,Meng X,Ren B,Li J,Chen J,Li W
Thu Feb 17 00:00:00 UTC 2022
Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation.
International journal of biological sciences
Sun N,Meng F,Zhao J,Li X,Li R,Han J,Chen X,Cheng W,Yang X,Kou Y,Zheng K,Yang J,Ikezoe T
Thu Mar 24 00:00:00 UTC 2022
Activation of Hippocampal IR/IRS-1 Signaling Contributes to the Treatment with Zuogui Jiangtang Jieyu Decoction on the Diabetes-Related Depression.
Evidence-based complementary and alternative medicine : eCAM
Yang H,Ling J,Meng P,Liu J,Lin X,Li W,Wang Y
Sun Apr 24 00:00:00 UTC 2022
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export.
Cell metabolism
Wang K,Huang W,Chen R,Lin P,Zhang T,Ni YF,Li H,Wu J,Sun XX,Geng JJ,Zhu YM,Nan G,Zhang W,Chen X,Zhu P,Bian H,Chen ZN
Tue Jan 05 00:00:00 UTC 2021
Gliquidone ameliorates hepatic insulin resistance in streptozotocin-induced diabetic Sur1-/- rats.
European journal of pharmacology
Zhang R,Zhou X,Sheng Q,Zhang Q,Xie T,Xu C,Zou Z,Dong J,Liao L
Sun Sep 05 00:00:00 UTC 2021
Gliquidone ameliorates hepatic insulin resistance in streptozotocin-induced diabetic Sur1-/- rats.
European journal of pharmacology
Zhang R,Zhou X,Sheng Q,Zhang Q,Xie T,Xu C,Zou Z,Dong J,Liao L
Sun Sep 05 00:00:00 UTC 2021
Mechanism of Mongolian Medicine Eerdun Wurile in Improving Postoperative Cognitive Dysfunction Through Activation of the PI3K Signaling Pathway.
Frontiers in neuroscience
Lv Z,Che L,Du Y,Yu J,Su E,Liu H,Chen D
Sat Apr 30 00:00:00 UTC 2022
ERα down-regulates carbohydrate responsive element binding protein and decreases aerobic glycolysis in liver cancer cells.
Journal of cellular and molecular medicine
Lu Y,Tian N,Hu L,Meng J,Feng M,Zhu Y,Zhang P,Li M,Liu Q,Tong L,Tong X,Li Y,Wu L
Thu Apr 01 00:00:00 UTC 2021
Effects of endurance training on the expression of host proteins involved in SARS-CoV-2 cell entry in C57BL/6J mouse.
Physiological reports
Tamura Y,Jee E,Kouzaki K,Kotani T,Nakazato K
Wed Sep 01 00:00:00 UTC 2021
Magnesium lithospermate B supplementation improved prenatal Bisphenol A exposure-induced metabolic abnormalities in male offspring.
Environmental toxicology
Huang WC,Liao KY,Hsieh SK,Pan PH,Kuan YH,Liao SL,Chen CJ,Chen WY
Wed Sep 01 00:00:00 UTC 2021
DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells.
Frontiers in pharmacology
Zhang X,Zhang Y,Zhou M,Xie Y,Dong X,Bai F,Zhang J
Fri Feb 04 00:00:00 UTC 2022
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Frontiers in pharmacology
Zhang Y,Fu Y,Jiang T,Liu B,Sun H,Zhang Y,Fan B,Li X,Qin X,Zheng Q
Wed Dec 15 00:00:00 UTC 2021
Metformin ameliorates skeletal muscle atrophy in Grx1 KO mice by regulating intramuscular lipid accumulation and glucose utilization.
Biochemical and biophysical research communications
Yang Y,Liao Z,Xiao Q
Thu Dec 17 00:00:00 UTC 2020
AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle.
Clinical science (London, England : 1979)
Chen M,Ji C,Yang Q,Gao S,Peng Y,Li Z,Gao X,Li Y,Jiang N,Zhang Y,Bian X,Chen C,Zhang K,Sanchis D,Yan F,Ye J
Fri Sep 18 00:00:00 UTC 2020
High-fat diet induced discrepant peripheral and central nervous systems insulin resistance in APPswe/PS1dE9 and wild-type C57BL/6J mice.
Aging
Guo Y,Ma X,Li P,Dong S,Huang X,Ren X,Yuan L
Thu Dec 03 00:00:00 UTC 2020
Frequent and mild scrotal heat stress in mice epigenetically alters glucose metabolism in the male offspring.
American journal of physiology. Endocrinology and metabolism
Wan X,He X,Liu Q,Wang X,Ding X,Li H
Sat Aug 01 00:00:00 UTC 2020
Chlorogenic Acid Stimulates the Thermogenesis of Brown Adipocytes by Promoting the Uptake of Glucose and the Function of Mitochondria.
Journal of food science
Han X,Zhang Y,Guo J,You Y,Zhan J,Huang W
Sun Dec 01 00:00:00 UTC 2019
Programmed death ligand 1 promotes lymph node metastasis and glucose metabolism in cervical cancer by activating integrin β4/SNAI1/SIRT3 signaling pathway.
Oncogene
Wang S,Li J,Xie J,Liu F,Duan Y,Wu Y,Huang S,He X,Wang Z,Wu X
Sun Jul 01 00:00:00 UTC 2018
