Proteintech

GMDS Polyclonal Antibody

GMDS Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 7

GMDS Antibody (15442-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 15442-1-AP (GMDS antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

GMDS Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

15442-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GMDS Fusion Protein Ag7319 (1-372 aa encoded by BC000117)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAHAPARCP SARGSGDGEM GKPRNVALIT GITGQDGSYL AEFLLEKGYE VHGIVRRSSS FNTGRIEHLY KNPQAHIEGN MKLHYGDLTD STCLVKIINE VKPTEIYNLG AQSHVKISFD LAEYTADVDG VGTLRLLDAV KTCGLINSVK FYQASTSELY GKVQEIPQKE TTPFYPRSPY GAAKLYAYWI VVNFREAYNL FAVNGILFNH ESPRRGANFV TRKISRSVAK IYLGQLECFS LGNLDAKRDW GHAKDYVEAM WLMLQNDEPE DFVIATGEVH SVREFVEKSF LHIGKTIVWE GKNENEVGRC KETGKVHVTV DLKYYRPTEV DFLQGDCTKA KQKLNWKPRV AFDELVREMV HADVELMRTN PNA (1-372 aa encoded by BC000117)

Target Information

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Glycomic Profiling Highlights Increased Fucosylation in Pseudomyxoma Peritonei.

Molecular & cellular proteomics : MCP

Saarinen L,Nummela P,Leinonen H,Heiskanen A,Thiel A,Haglund C,Lepistö A,Satomaa T,Hautaniemi S,Ristimäki A

Thu Nov 01 00:00:00 UTC 2018

Glycomic Profiling Highlights Increased Fucosylation in Pseudomyxoma Peritonei.

Molecular & cellular proteomics : MCP

Saarinen L,Nummela P,Leinonen H,Heiskanen A,Thiel A,Haglund C,Lepistö A,Satomaa T,Hautaniemi S,Ristimäki A

Thu Nov 01 00:00:00 UTC 2018

High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery.

Cell chemical biology

Kizuka Y,Funayama S,Shogomori H,Nakano M,Nakajima K,Oka R,Kitazume S,Yamaguchi Y,Sano M,Korekane H,Hsu TL,Lee HY,Wong CH,Taniguchi N

Thu Jul 21 00:00:00 UTC 2016

High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery.

Cell chemical biology

Kizuka Y,Funayama S,Shogomori H,Nakano M,Nakajima K,Oka R,Kitazume S,Yamaguchi Y,Sano M,Korekane H,Hsu TL,Lee HY,Wong CH,Taniguchi N

Thu Jul 21 00:00:00 UTC 2016

GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity.

Molecular and cellular biology

Bisht KK,Dudognon C,Chang WG,Sokol ES,Ramirez A,Smith S

Wed Aug 01 00:00:00 UTC 2012

GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity.

Molecular and cellular biology

Bisht KK,Dudognon C,Chang WG,Sokol ES,Ramirez A,Smith S

Wed Aug 01 00:00:00 UTC 2012

GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity.

Molecular and cellular biology

Bisht KK,Dudognon C,Chang WG,Sokol ES,Ramirez A,Smith S

Wed Aug 01 00:00:00 UTC 2012

GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity.

Molecular and cellular biology

Bisht KK,Dudognon C,Chang WG,Sokol ES,Ramirez A,Smith S

Wed Aug 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: GDP-D-mannose dehydratase; GDP-mannose 4,6 dehydratase; GMD; RP1-118B18.1; short chain dehydrogenase/reductase family 3E, member 1

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Gene Aliases: BC031788; C87208; GMD; GMDS; SDR3E1

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UniProt ID: (Human) O60547, (Mouse) Q8K0C9

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Entrez Gene ID: (Human) 2762, (Mouse) 218138, (Rat) 291095

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Function(s)

protein binding GDP-mannose 4,6-dehydratase activity NADP+ binding catalytic activity lyase activity coenzyme binding

Process(es)

Notch signaling pathway GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GMDS Polyclonal Antibody

GMDS Antibody (15442-1-AP) in ICC/IF

Product Details

15442-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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