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GMFG Polyclonal Antibody

GMFG Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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GMFG Antibody (13625-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using 13625-1-AP (GMFG antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

GMFG Antibody in Immunoprecipitation (IP)

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Product Details

13625-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GMFG Fusion Protein Ag4538 (1-141 aa encoded by BC032819)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SDSLVVCEV DPELTEKLRK FRFRKETDNA AIIMKVDKDR QMVVLEEEFQ NISPEELKME LPERQPRFVV YSYKYVHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNR LVQTAELTKV FEIRTTDDLT EAWLQEKLSF FR (1-141 aa encoded by BC032819)

Target Information

Glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may be involved in glial differentiation, neural regeneration, and inhibition of tumor cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Upregulation of lncRNA LANCL1-AS1 inhibits the progression of non-small-cell lung cancer via the miR-3680-3p/GMFG axis.

Open medicine (Warsaw, Poland)

Pan H,Peng J,Qiao X,Gao H

Wed Mar 22 00:00:00 UTC 2023

RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression.

Medical oncology (Northwood, London, England)

Zhang YL,Cao JL,Zhang Y,Liao L,Deng L,Yang SY,Hu SY,Ning Y,Zhang FL,Li DQ

Tue Feb 01 00:00:00 UTC 2022

The Actin-Disassembly Protein Glia Maturation Factor γ Enhances Actin Remodeling and B Cell Antigen Receptor Signaling at the Immune Synapse.

Frontiers in cell and developmental biology

Deretic N,Bolger-Munro M,Choi K,Abraham L,Gold MR

Tue Aug 03 00:00:00 UTC 2021

The Actin-Disassembly Protein Glia Maturation Factor γ Enhances Actin Remodeling and B Cell Antigen Receptor Signaling at the Immune Synapse.

Frontiers in cell and developmental biology

Deretic N,Bolger-Munro M,Choi K,Abraham L,Gold MR

Tue Aug 03 00:00:00 UTC 2021

GMFG Has Potential to Be a Novel Prognostic Marker and Related to Immune Infiltrates in Breast Cancer.

Frontiers in oncology

Yang Y,He X,Tang QQ,Shao YC,Song WJ,Gong PJ,Zeng YF,Huang SR,Zhou JY,Wan HF,Wei L,Zhang JW

Tue Aug 10 00:00:00 UTC 2021

Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.

Oncology reports

Wang H,Chen Z,Chang H,Mu X,Deng W,Yuan Z,Yao F,Liu Y,Mai R,Wu B

Wed Feb 01 00:00:00 UTC 2017

Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.

Oncology reports

Wang H,Chen Z,Chang H,Mu X,Deng W,Yuan Z,Yao F,Liu Y,Mai R,Wu B

Wed Feb 01 00:00:00 UTC 2017

Coronary veins determine the pattern of sympathetic innervation in the developing heart.

Development (Cambridge, England)

Nam J,Onitsuka I,Hatch J,Uchida Y,Ray S,Huang S,Li W,Zang H,Ruiz-Lozano P,Mukouyama YS

Mon Apr 01 00:00:00 UTC 2013

Coronary veins determine the pattern of sympathetic innervation in the developing heart.

Development (Cambridge, England)

Nam J,Onitsuka I,Hatch J,Uchida Y,Ray S,Huang S,Li W,Zang H,Ruiz-Lozano P,Mukouyama YS

Mon Apr 01 00:00:00 UTC 2013

Glia maturation factor gamma regulates the migration and adherence of human T lymphocytes.

BMC immunology

Lippert DN,Wilkins JA

Wed Apr 18 00:00:00 UTC 2012

Glia maturation factor gamma regulates the migration and adherence of human T lymphocytes.

BMC immunology

Lippert DN,Wilkins JA

Wed Apr 18 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: Glia maturation factor gamma; glia maturation factor, gamma; GMF-gamma

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Gene Aliases: 0610039G16Rik; 2310057N07Rik; AI324845; GMF-GAMMA; GMFG

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UniProt ID: (Human) O60234, (Rat) Q80T18, (Mouse) Q9ERL7

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Entrez Gene ID: (Human) 9535, (Rat) 113940, (Mouse) 63986

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Function(s)

actin binding protein kinase inhibitor activity enzyme activator activity growth factor activity Arp2/3 complex binding kinase regulator activity

Process(es)

negative regulation of Arp2/3 complex-mediated actin nucleation regulation of phosphorylation regulation of actin cytoskeleton reorganization protein phosphorylation negative regulation of protein kinase activity positive regulation of catalytic activity

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GMFG Polyclonal Antibody

GMFG Antibody (13625-1-AP) in IHC (P)

Product Details

13625-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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