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Product Details
H00051053-M01J
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1A8
Immunogen
GMNN (AAH05185.1, 110 a.a. approximately 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: LYEALKENEK LHKEIEQKDN EIARLKKENK ELAEVAEHVQ YMAELIERLN GEPLDNFESL DNQEFDSEEE TVEDSLVEDS EIGTCAEGTV SSSTDAKPCI
Target Information
GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Geminin; Geminin GMNN; OTTHUMP00000039393; RP3 369A17.3
Gene Aliases: Gem; GMNN; MGORS6
UniProt ID: (Human) O75496
Entrez Gene ID: (Human) 51053
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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