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Immunogen sequence: MKALILVGG YGTRLRPLTL STPKPLVDFC NKPILLHQVE ALAAAGVDHV ILAVSYMSQV LEKEMKAQEQ RLGIRISMSH EEEPLGTAGP LALARDLLSE TADPFFVLNS DVICDFPFQA MVQFHRHHGQ EGSILVTKVE EPSKYGVVVC EADTGRIHRF VEKPQVFVSN KINAGMYILS PAVLRRIQLQ PTSIEKEVFP IMAKEGQLYA MELQGFWMDI GQPKDFLTGM CLFLQSLRQK QPERLCSGPG IVGNVLVDPS ARIGQNCSIG PNVSLGPGVV VEDGVCIRRC TVLRDARIRS HSWLESCIVG WRCRVGQWVR MENVTVLGED VIVNDELYLN GASVLPHKSI GESVPEPRII M (1-360 aa encoded by BC001141)
This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2.7.7.13; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; mannose-1-phosphate guanyltransferase beta; Mannose-1-phosphate guanylyltransferase catalytic subunit beta
Gene Aliases: AI317178; E430010H19; GMPPB; MDDGA14; MDDGB14; MDDGC14; RGD1560458
UniProt ID: (Human) Q9Y5P6, (Mouse) Q8BTZ7
Entrez Gene ID: (Human) 29925, (Rat) 363145, (Mouse) 331026
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