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Invitrogen
GNB5 Polyclonal Antibody
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Product Details
PA1-12707
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the D1 blade of the G 5 protein.
Conjugate
Form
Liquid
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2109641
Product Specific Information
A suggested positive control for this product is plasma membranes from rat cerebrum.
Target Information
The Gb5 protein is a G protein subunit present predominantly in the central nervous system. This protein appears to be expressed in two forms, one found in the brain of 39 kDa and one found in the retina of 44 kDa. It has also been found that Gb5 associates tightly with RGS7, a member of the superfamily of negative regulators of G protein signaling. These complexes have been localized to most regions of the brain, whereas Gb1-4 exhibit no observable colocalization with RGS7, despite their widespread codistribution throughout similar neuronal networks. This antibody is specific for a peptide sequence within the D1 blade which is not found in the Gb's 1-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: flail; flailer; G protein, beta subunit 5L; G protein, beta-5 subunit; GBB5; Gbeta5; guanine nucleotide binding protein (G protein), beta 5; guanine nucleotide binding protein (G protein), beta polypeptide 5; guanine nucleotide binding protein, beta 5; Guanine nucleotide-binding protein subunit beta-5; guanine nucleotide-binding protein, beta subunit 5L; guanine nucleotide-binding protein, beta-5 subunit; hug; Transducin beta chain 5
Gene Aliases: flr; GB5; Gbeta5; GBS; GNB5
UniProt ID: (Human) O14775, (Mouse) P62881, (Rat) P62882
Entrez Gene ID: (Human) 10681, (Mouse) 14697, (Rat) 83579
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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