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Invitrogen
GNG8 Polyclonal Antibody
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Product Details
PA5-68207
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human GNG8.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.3, with 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691950
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the βγ subunits. It is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the γ as well as the α and β subunits and that preferential associations between members of subunit families increase G protein functional diversity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein gamma 8 subunit; Gamma-9; Ggamma 9; Ggamma9; guanine nucleotide binding protein (G protein), gamma 8; guanine nucleotide binding protein (G protein), gamma 8 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
Gene Aliases: G(y)8; GNG8; GNG9; GNGT9
UniProt ID: (Human) Q9UK08, (Rat) P63077, (Mouse) P63078
Entrez Gene ID: (Human) 94235, (Rat) 245986, (Mouse) 14709
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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