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Invitrogen
GNPAT Polyclonal Antibody
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Product Details
PA5-36447
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 341-390 of human GNPAT
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2553530
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 77 kDa.
Purity is >95% by SDS-PAGE.
Target Information
GNPAT is a key enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata type 2, which is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acyl-CoA:dihydroxyacetonephosphate acyltransferase; Acyl-CoA:dihydroxyacetonephosphateacyltransferase; DAP-AT; DHAP-AT; Dihydroxyacetone phosphate acyltransferase; Glycerone-phosphate O-acyltransferase
Gene Aliases: AU019525; D1Ertd819e; DAP-AT; DAPAT; DHAPAT; GNPAT; RCDP2
UniProt ID: (Human) O15228, (Mouse) P98192, (Rat) Q9ES71
Entrez Gene ID: (Human) 8443, (Mouse) 14712, (Rat) 84470
glycerophospholipid metabolic process
phosphatidic acid biosynthetic process
synapse assembly
response to nutrient
ether lipid biosynthetic process
cerebellum morphogenesis
paranodal junction assembly
response to drug
response to starvation
membrane organization
response to fatty acid
metabolic process
myelination
cellular lipid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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