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Invitrogen
GNPNAT1 Polyclonal Antibody
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Product Details
PA5-120578
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-91 of human GNPNAT1 (NP_932332.1).
Conjugate
Form
Liquid
Concentration
2.72 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2914150
Product Specific Information
Positive test controls include: HT-29, LO2, BxPC-3, mouse kidney, mouse lung, rat liver, rat kidney.
Immunogen sequence: MKPDETPMFD PSLLKEVDWS QNTATFSPAI SPTHPGEGLV LRPLCTADLN RGFFKVLGQL TETGVVSPEQ FMKSFEHMKK SGDYYVTVVE D
Target Information
Glucosamine-6 phosphate-N-acetyl Transferase (GNPNAT1) is a key enzyme in the hexosamine biosynthetic pathway. It converts D-glucosamine 6-phosphate to N-acetyl-D-glucosamine 6-phosphate, the acetylation step allowing carbon and nitrogen enter into the hexosamine biosynthetic pathway. Recently inhibition of GNPNAT1 has been reported to promote proliferation and aggressiveness of castration-resistant prostate cancer. (27194471).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glucosamine 6-phosphate N-acetyltransferase; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase 1; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase; Protein EMeg32
Gene Aliases: AU017428; AU040593; EMeg32; GNA1; GNPNAT; GNPNAT1; Gpnat1; Gsnpat; RGD1563144
UniProt ID: (Human) Q96EK6, (Mouse) Q9JK38
Entrez Gene ID: (Human) 64841, (Mouse) 54342, (Rat) 498486
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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