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Proteintech
GNS Polyclonal Antibody
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Product Details
13044-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GNS Fusion Protein Ag3712 (200-552 aa encoded by BC012482)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SVDYLTDVL ANVSLDFLDY KSNFEPFFMM IATPAPHSPW TAAPQYQKAF QNVFAPRNKN FNIHGTNKHW LIRQAKTPMT NSSIQFLDNA FRKRWQTLLS VDDLVEKLVK RLEFTGELNN TYIFYTSDNG YHTGQFSLPI DKRQLYEFDI KVPLLVRGPG IKPNQTSKML VANIDLGPTI LDIAGYDLNK TQMDGMSLLP ILRGASNLTW RSDVLVEYQG EGRNVTDPTC PSLSPGVSQC FPDCVCEDAY NNTYACVRTM SALWNLQYCE FDDQEVFVEV YNLTADPDQI TNIAKTIDPE LLGKMNYRLM MLQSCSGPTC RTPGVFDPGY RFDPRLMFSN RGSVRTRRFS KHLL (200-552 aa encoded by B C012482)
Target Information
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G6S; glucosamine -6-sulfatase; Glucosamine-6-sulfatase; N-acetylglucosamine-6-sulfatase
Gene Aliases: 2610016K11Rik; AU042285; C87209; G6S; GNS; N28088
UniProt ID: (Human) P15586, (Mouse) Q8BFR4
Entrez Gene ID: (Human) 2799, (Mouse) 75612, (Rat) 299825
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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