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Invitrogen
GNS Polyclonal Antibody
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FIGURE: 1 / 2
GNS Antibody (PA5-95512) in WB
Western blot analysis of GNS in Lane 1: rat lung tissue lysates, Lane 2: rat kidney tissue lysates, Lane 3: rat testis tissue lysates, Lane 4: rat PC-12 whole cell lysates, Lane 5: mouse lung tissue lysates, Lane 6: mouse kidney tissue lysates, Lane 7: mouse testis tissue lysates, Lane 8: mouse spleen tissue lysates, Lane 9: mouse thymus tissue lysates. Electrophoresis was performed with 5-20% SDS-PAGE gel (70V, Stacking gel; 90V Resolving gel, Time: 2-3 hours), transferred to a nitrocellulose membrane and blocked using 5% Non-fat Milk/TBS... View More
Product Details
PA5-95512
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human GNS recombinant protein (Position: W238-R355).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2807314
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HepG2 whole cell, human PANC-1 whole cell, human SGC-7901 whole cell, rat lung tissue, rat kidney tissue, rat testis tissue, rat PC-12 whole cell, mouse lung tissue, mouse kidney tissue, mouse testis tissue, mouse spleen tissue, mouse thymus tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G6S; glucosamine -6-sulfatase; Glucosamine-6-sulfatase; N-acetylglucosamine-6-sulfatase
Gene Aliases: 2610016K11Rik; AU042285; C87209; G6S; GNS; N28088
UniProt ID: (Human) P15586, (Mouse) Q8BFR4
Entrez Gene ID: (Human) 2799, (Mouse) 75612, (Rat) 299825
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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