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Proteintech
GORAB Polyclonal Antibody
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Product Details
17798-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GORAB Fusion Protein Ag12002 (1-264 aa encoded by BC064945)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSWAAVLAV AAARFGHFWG CRWPGPMAQG WAGFSEEELR RLKQTKDPFE PQRRLPAKKS RQQLQREKAL VEQSQKLGLQ DGSTSLLPEQ LLSAPKQRVN VQKPPFSSPT LPSHFTLTSP VGDGQPQGIE SQPKELGLEN SHDGHNNVEI LPPKPDCKLE KKKVELQEKS RWEVLQQEQR LMEEKNKRKK ALLAKAIAER SKRTQAETMK LKRIQKELQA LDDMVSADIG ILRNRIDQAS LDYSYAR (1-264 aa encoded by BC064945)
Target Information
TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dynactin 1, isoform 1; dynactin 1 (p150, Glued homolog); p150, Glued homolog; 150 kDa dynein-associated polypeptide; p150-glued; golgin, RAB6-interacting; hNTKL-BP1; mNTKL-BP1; N-terminal kinase-like-binding protein 1; NTKL-binding protein 1; NTKL-BP1; RAB6-interacting golgin; SCY1-like 1 binding protein 1; SCY1-like 1-binding protein 1; SCYL1-binding protein 1; SCYL1-BP1
Gene Aliases: AI467484; GO; GORAB; NTKL-BP1; NTKLBP1; SCYL1BP1
UniProt ID: (Human) Q5T7V8, (Rat) B1H222, (Mouse) Q8BRM2
Entrez Gene ID: (Human) 92344, (Rat) 304923, (Mouse) 98376
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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