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GP340 Antibody (PA5-115313) in ICC/IF
Immunocytochemistry analysis of GP340 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115313) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Product Details
PA5-115313
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DMBT1(Accession Q9UGM3), corresponding to amino acid residues C2360-E2410.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2899949
Product Specific Information
Antibody detects endogenous levels of total gp340.
Target Information
Glycoprotein-340 is member of the scavenger receptor superfamily and has been identified as a putative SP-D receptor. Gp-340 has been shown to bind SP-D in a calcium dependent manner through a protein-protein interaction. Like SP-D, gp-340 is mainly found in lung tissue and immunohistochemistry revealed high expression in alveolar macrophages. An identical protein is present in saliva (salivary agglutinin) and both forms are encoded by the gene DMBT1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apactin; CRP-ductin; Deleted in malignant brain tumors 1 protein; deleted in malignant brain tumors 1 pseudogene; Ebnerin; Glycoprotein 300; Glycoprotein 340; Gp-340; gp300; Hensin; Mucin-like glycoprotein; Muclin; p80; Pancrin; RP11-481L19.1; SAG; Salivary agglutinin; Scavenger receptor cysteine-rich domain-containing protein DMBT1; Surfactant pulmonary-associated D-binding protein; Vomeroglandin
Gene Aliases: CRP; CRP-[a]; CRP-[b]; Crpd; DBMT1; DMBT1; gp300; GP340; muclin; p80; SAG
UniProt ID: (Human) Q9UGM3, (Rat) Q8CIZ5, (Mouse) Q60997
Entrez Gene ID: (Human) 1755, (Rat) 170568, (Mouse) 12945
blastocyst development
inner cell mass cell proliferation
receptor-mediated endocytosis
multicellular organism development
response to wounding
response to organic substance
protein transport
cell differentiation
positive regulation of epithelial cell differentiation
tissue regeneration
response to estrogen
transport
pattern recognition receptor signaling pathway
epithelial cell differentiation
induction of bacterial agglutination
cellular protein metabolic process
innate immune response
defense response to virus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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