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Invitrogen
GPBB Polyclonal Antibody
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Product Details
PA5-92950
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 544-843 of human PYGB (NP_0028532)
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806557
Product Specific Information
Immunogen sequence: LKFSAFLEKE YKVKINPSSM FDVHVKRIHE YKRQLLNCLH VVTLYNRIKR DPAKAFVPRT VMIGGKAAPG YHMAKLIIKL VTSIGDVVNH DPVVGDRLKV IFLENYRVSL AEKVIPAADL SQQISTAGTE ASGTGNMKFM LNGALTIGTM DGANVEMAEE AGAENLFIFG LRVEDVEALD RKGYNAREYY DHLPELKQAV DQISSGFFSP KEPDCFKDIV NMLMHHDRFK VFADYEAYMQ CQAQVDQLYR NPKEWTKKVI RNIACSGKFS SDRTITEYAR EIWGVEPSDL QIPPPNIPRD; Positive Samples: BT-474, SW620, HT-29, HepG2, Mouse brain, Mouse heart, Mouse lung, Rat brain, Rat heart
Target Information
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain glycogen phosphorylase; glycogen phosphorylase B; Glycogen phosphorylase, brain form; MGC9213
Gene Aliases: GLYPHOA; GPBB; PYGB
UniProt ID: (Human) P11216, (Mouse) Q8CI94, (Rat) P53534
Entrez Gene ID: (Human) 5834, (Mouse) 110078, (Rat) 25739
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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