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Invitrogen
GPD1L Polyclonal Antibody
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GPD1L Antibody (PA5-24216) in IHC (P)
Immunohistochemistry analysis of GPD1L in formalin fixed and paraffin embedded mouse heart tissue. Samples were incubated with GPD1L polyclonal antibody (Product # PA5-24216) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-24216
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human GPD1L
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2541716
Target Information
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Glycerol-3-phosphate dehydrogenase 1-like protein; GPD1-L
Gene Aliases: 2210409H23Rik; D9Ertd660e; GPD1-L; GPD1L; KIAA0089
UniProt ID: (Human) A8K9U3, (Mouse) Q3ULJ0
Entrez Gene ID: (Human) 23171, (Mouse) 333433
regulation of heart rate
carbohydrate metabolic process
glycerol-3-phosphate metabolic process
NADH metabolic process
positive regulation of sodium ion transport
NAD metabolic process
negative regulation of peptidyl-serine phosphorylation
glycerol-3-phosphate catabolic process
oxidation-reduction process
regulation of ventricular cardiac muscle cell membrane depolarization
ventricular cardiac muscle cell action potential
negative regulation of protein kinase C signaling
positive regulation of protein localization to cell surface
regulation of sodium ion transmembrane transporter activity
phosphatidic acid biosynthetic process
triglyceride biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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