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Proteintech
GPD2 Monoclonal Antibody (1C12E2)
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Product Details
68174-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1C12E2
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: KAVKGTLVGG GALATVLGLS QFAHYRRKQM NLAYVKAADC ISEPVNREPP SREAQLLTLQ NTSEFDILVI GGGATGSGCA LDAVTRGLKT ALVERDDFSS GTSSRSTKLI HGGVRYLQKA IMKLDIEQYR MVKEALHERA NLLEIAPHLS APLPIMLPVY KWWQLPYYWV GIKLYDLVAG SNCLKSSYVL SKSRALEHFP MLQKDKLVGA IVYYDGQHND ARMNLAIALT AARYGAATAN YMEVVSLLKK TDPQTGKVHV SGARCKDVLT GQEFDVRAKC VINATGPFTD SVRKMDDKDA AAICQPSAGV HIVMPGYYSP ESMGLLDPAT SDGRVIFFLP WQKMTIAGTT DTPTDVTHHP IPSEEDINFI LNEV
Target Information
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FAD-linked glycerol-3-phosphate dehydrogenase; glycerol phosphate dehydrogenase 1, mitochondrial; Glycerol-3-phosophate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase 2, mitochondrial; Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mGDH; mitochondrial glycerol-3-phosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase; mitohondrial glycerophosphate dehydrogenase gene; mtGPD; mtGPDH gene, promoter region and alternative transcripts; Protein TISP38; testicular tissue protein Li 76
Gene Aliases: AA408484; AI448216; AU021455; AW494132; GDH2; Gdm1; Gpd-m; GPD2; GPDH; Gpdh-m; GPDM; mGPDH; mtGPDH; TISP38
UniProt ID: (Human) P43304, (Mouse) Q64521, (Rat) P35571
Entrez Gene ID: (Human) 2820, (Mouse) 14571, (Rat) 25062
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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