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Abnova
GPI Polyclonal Antibody, MaxPab™
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Product Details
H00002821-B01P
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GPI (AAH04982.1, 1 a.a. approximately 558 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAALTRDPQF QKLQQWYREH RSELNLRRLF DANKDRFNHF SLTLNTNHGH ILVDYSKNLV TEDVMRMLVD LAKSRGVEAA RERMFNGEKI NYTEGRAVLH VALRNRSNTP ILVDGKDVMP EVNKVLDKMK SFCQRVRSGD WKGYTGKTIT DVINIGIGGS DLGPLMVTEA LKPYSSGGPR VWYVSNIDGT HIAKTLAQLN PESSLFIIAS KTFTTQETIT NAETAKEWFL QAAKDPSAVA KHFVALSTNT TKVKEFGIDP QNMFEFWDWV GGRYSLWSAI GLSIALHVGF DNFEQLLSGA HWMDQHFRTT PLEKNAPVLL ALLGIWYINC FGCETHAMLP YDQYLHRFAA YFQQGDMESN GKYITKSGTR VDHQTGPIVW GEPGTNGQHA FYQLIHQGTK MIPCDFLIPV QTQHPIRKGL HHKILLANFL AQTEALMRGK STEEARKELQ AAGKSPEDLE RLLPHKVFEG NRPTNSIVFT KLTPFMLGAL VAMYEHKIFV QGIIWDINSF DQWGVELGKQ LAKKIEPELD GSAQVTSHDA STNGLINFIK QQREARVQ
Target Information
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMF; Autocrine motility factor; glucose phosphate isomerase; Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase {ECO:0000250|UniProtKB:P06745}; GPI; GPI {ECO:0000250|UniProtKB:P06745}; gpi {ECO:0000312|RGD:2727}; hexose monophosphate isomerase; hexosephosphate isomerase; Neuroleukin; neuroleukin {ECO:0000250|UniProtKB:P06745}; NLK; NLK {ECO:0000250|UniProtKB:P06745}; oxoisomerase; PGI; PGI {ECO:0000250|UniProtKB:P06745}; PHI; PHI {ECO:0000250|UniProtKB:P06745}; Phosphoglucose isomerase; phosphoglucose isomerase {ECO:0000250|UniProtKB:P06745}; phosphohexomutase; Phosphohexose isomerase; phosphohexose isomerase {ECO:0000250|UniProtKB:P06745}; phosphosaccharomutase; SA-36; sperm antigen; Sperm antigen 36; sperm antigen-36
Gene Aliases: AMF; GNPI; GPI; Gpi1; NLK; PGI; PHI; SA-36; SA36
UniProt ID: (Human) P06744, (Rat) Q6P6V0
Entrez Gene ID: (Human) 2821, (Rat) 292804
angiogenesis
in utero embryonic development
mesoderm formation
carbohydrate metabolic process
gluconeogenesis
humoral immune response
hemostasis
learning or memory
methylglyoxal biosynthetic process
erythrocyte homeostasis
glucose homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
aldehyde catabolic process
glucose 6-phosphate metabolic process
canonical glycolysis
glycolytic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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