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Invitrogen
GPM6A Polyclonal Antibody
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FIGURE: 1 / 3
GPM6A Antibody (720252) in WB
Western blot was performed using Anti-GPM6A Polyclonal Antibody, (Product # 720252) and a 30 kDa band corresponding to GPM6A was observed across tissues tested except in Mouse Liver, Mouse Skeletal Muscle, Rat Liver and Rat Skeletal Muscle which are reported to be negative. Tissue extracts (30 µg lysate) of Mouse Brain (Lane 1), Mouse Cerebellum (Lane 2), Rat Brain (Lane 3), and Rat Cerebellum (Lane 4), Mouse Liver (Lane 5), Mouse Skeletal Muscle (Lane 6), Rat Liver (Lane 7), Rat Skeletal Muscle (Lane 8) were electrophoresed using Novex® N... View More
Product Details
720252
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptides corresponding to Human GPM6A (aa 257-274, 2-11)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 0.1% BSA, 30% glycerol
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2633216
Product Specific Information
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Horse, Bovine and Dog
Target Information
Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: M6a; Neuronal membrane glycoprotein M6-a
Gene Aliases: GPM6; GPM6A; M6A
UniProt ID: (Human) P51674, (Mouse) P35802, (Rat) Q812E9
Entrez Gene ID: (Human) 2823, (Mouse) 234267, (Rat) 306439
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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