Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
GPN1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
15752-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GPN1 Fusion Protein Ag8252 (66-374 aa encoded by BC007451)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ANIDIRDTV KYKEVMKQYG LGPNGGIVTS LNLFATRFDQ VMKFIEKAQN MSKYVLIDTP GQIEVFTWSA SGTIITEALA SSFPTVVIYV MDTSRSTNPV TFMSNMLYAC SILYKTKLPF IVVMNKTDII DHSFAVEWMQ DFEAFQDALN QETTYVSNLT RSMSLVLDEF YSSLRVVGVS AVLGTGLDEL FVQVTSAAEE YEREYRPEYE RLKKSLANAE SQQQREQLER LRKDMGSVAL DAGTAKDSLS PVLHPSDLIL TRGTLDEEDE EADSDTDDID HRVTEESHEE PAFQNFMQES MAQYWKRNNK (66-374 aa encoded by BC007451)
Target Information
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ATP(GTP)-binding protein; GPN-loop GTPase 1; MBD2-interacting protein; MBDin; methyl-CpG binding domain protein 2 interacting protein; RNA polymerase II associated protein 4; RNAPII-associated protein 4; XPA binding protein 1; XPA binding protein 1, GTPase; XPA-binding protein 1
Gene Aliases: 2410004J02Rik; AI449615; ATPBD1A; GPN1; HUSSY-23; MBDIN; NTPBP; RPAP4; XAB1
UniProt ID: (Human) Q9HCN4, (Mouse) Q8VCE2
Entrez Gene ID: (Human) 11321, (Mouse) 74254
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support