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Invitrogen
GPN1 Polyclonal Antibody
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Product Details
PA5-36009
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human GPN1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2553319
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Predicted reactivity: Mouse (91%), Rat (90%), Zebrafish (80%), Bovine (94%).
Target Information
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP(GTP)-binding protein; GPN-loop GTPase 1; MBD2-interacting protein; MBDin; methyl-CpG binding domain protein 2 interacting protein; RNA polymerase II associated protein 4; RNAPII-associated protein 4; XPA binding protein 1; XPA binding protein 1, GTPase; XPA-binding protein 1
Gene Aliases: 2410004J02Rik; AI449615; ATPBD1A; GPN1; HUSSY-23; MBDIN; NTPBP; RPAP4; XAB1
UniProt ID: (Human) Q9HCN4, (Mouse) Q8VCE2
Entrez Gene ID: (Human) 11321, (Mouse) 74254
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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