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Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (95%); Gibbon, Marmoset (89%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G protein-coupled receptors mediate extracellular signals into intracellular signals (G protein activation). They respond to a wide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are usually integral seven pass membrane proteins with some conserved amino acid regions. GPR-152 (G proteincoupled receptor 152) is a 511 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. Encoded by a gene on human chromosome 11q13.2 and mouse chromosome 19 A, GPR-152 may function as an orphan receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor PGR5; G-protein coupled receptor PGR5; Probable G-protein coupled receptor 152
Gene Aliases: GPR152; PGR5
UniProt ID: (Human) Q8TDT2
Entrez Gene ID: (Human) 390212
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