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Product Details
PA5-32852
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GPR3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550314
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Horse (94%); Bovine, Rabbit (88%); Elephant, Panda, Pig (82%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1, 000 members and is the largest known class of molecular targets with proven therapeutic value. GPR3 is an orphan receptor with constitutive G signaling activity. GPR3 modulates a number of brain functions, including behavioral responses to stress, neurite outgrowth and amyloid-beta peptide generation suggesting that it may play a role in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACCA orphan receptor; adenylate cyclase constitutive activator; G-protein coupled receptor 3; Hacca; OTTHUMP00000043209
Gene Aliases: ACCA; GPR3
UniProt ID: (Human) P46089
Entrez Gene ID: (Human) 2827
Performance Guarantee
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