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Alomone Labs, LTD
GPR39 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 4
GPR39 (extracellular) Antibody (AGR-045-200UL) in WB
Western blot analysis of human HT-29 colorectal adenocarcinoma (lanes 1 and 3) and human MEG-01 megakaryoblastic leukemia (lanes 2 and 4)cell line lysates: - 1,2 Anti-GPR39 (extracellular) Antibody (#AGR-045), (1:200).3,4. Anti-GPR39 (extracellular) Antibody , preincubated with GPR39 (extracellular) Blocking Peptide (#BLP-GR045).
Product Details
AGR-045-200UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KPKHDWTRTYFR, corresponding to amino acid residues 309-320 of mouse GPR39, 3rd extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. G protein-coupled receptor 39 is an orphan receptor in the Ghrelin family pathway. Various studies have shown that GPR39 plays important roles in hypertension, adipogenesis and that overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor 39
Gene Aliases: 4933415E13Rik; GPR39
UniProt ID: (Human) O43194
Entrez Gene ID: (Human) 2863, (Mouse) 71111, (Rat) 288995
diet induced thermogenesis
signal transduction
G-protein coupled receptor signaling pathway
adult feeding behavior
regulation of lipid metabolic process
positive regulation of insulin secretion
gastric emptying
positive regulation of insulin secretion involved in cellular response to glucose stimulus
regulation of membrane potential
glucose homeostasis
cholesterol homeostasis
positive regulation of release of sequestered calcium ion into cytosol
negative regulation of gastric acid secretion
cellular response to zinc ion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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