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Invitrogen
GPR41 Polyclonal Antibody
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Product Details
PA5-75521
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Bovine,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 61-106 of Human GPR41.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719249
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPRs translate extracellular signals into intracellular signals (a process called G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR41 (G-protein coupled receptor 41), also known as FFAR3 (Free fatty acid receptor 3), is a 346 amino acid multi-pass membrane protein that belongs to the G protein-coupled receptor family. Expressed at high levels in adipose tissue and at lower levels throughout the body, GPR41 functions as a receptor for short chain fatty acids via elevation of intracellular calcium levels and inhibition of adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Free fatty acid receptor 3; G protein-coupled receptor 41; G-protein coupled receptor 41; Gpcr41; putative G protein-coupled receptor GPR41
Gene Aliases: FFA3R; FFAR3; Gm478; GPR41; GPR42
UniProt ID: (Human) O14843, (Rat) B2GV46, (Mouse) Q3UFD7
Entrez Gene ID: (Human) 2865, (Rat) 365228, (Mouse) 233080
mucosal immune response
positive regulation of cytokine production involved in immune response
positive regulation of acute inflammatory response to non-antigenic stimulus
regulation of heart rate by chemical signal
inflammatory response
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
regulation of norepinephrine secretion
positive regulation of chemokine production
glucose homeostasis
positive regulation of action potential
negative regulation of blood pressure
regulation of hormone biosynthetic process
cellular response to fatty acid
regulation of peptide hormone secretion
positive regulation of glucose import in response to insulin stimulus
immune system process
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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