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Alomone Labs, LTD
GPR43/FFAR2 Polyclonal Antibody
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FIGURE: 1 / 4
GPR43/FFAR2 Antibody (AFR-032-200UL) in IHC (F)
Expression of GPR43/FFAR2 in rat hippocampus. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-GPR43/FFAR2 Antibody (#AFR-032), (1:300), followed by goat Anti-rabbit-AlexaFluor-488. A. Staining in the rat hippocampal dentate gyrus region showed FFAR2 immunoreactivity (green) in astrocyte outlines (arrows) most intensely in the hilus (H). B. Pre-incubation of the Antibody w... View More
Product Details
AFR-032-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RGAEETVEGTKTDR, corresponding to amino acid residues 301-314 of rat FFAR2, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; Leukocyte-specific STAT-induced GPCR
Gene Aliases: Ffar2; GPCR43; Gpr43; Lssig
UniProt ID: (Rat) Q76EI6, (Mouse) Q8VCK6
Entrez Gene ID: (Rat) 292794, (Mouse) 233079
leukocyte chemotaxis involved in inflammatory response
mucosal immune response
regulation of acute inflammatory response
positive regulation of cytokine production involved in immune response
cell surface pattern recognition receptor signaling pathway
positive regulation of acute inflammatory response to non-antigenic stimulus
G-protein coupled receptor signaling pathway
biological_process
lipid storage
positive regulation of chemokine production
glucose homeostasis
fat cell differentiation
cellular response to fatty acid
regulation of peptide hormone secretion
positive regulation of interleukin-8 secretion
immune system process
inflammatory response
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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