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Invitrogen
GPR6 Polyclonal Antibody
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GPR6 Antibody (PA1-147) in IHC (P)
Immunohistochemistry analysis of GPR6 was performed on human ileum mucosa tissue. To expose target proteins, antigen retrieval was performed by microwaving tissues for 20 minutes in 10mM sodium citrate buffer (pH 6.0). Tissue slides were probed with a GPR6 polyclonal antibody (Product # PA1-147) at a dilution of 1:1000, overnight at 4C in a humidified chamber without (left panel) or with peptide blocking co... View More
Product Details
PA1-147
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated Cys-FQSKVPFRSRSPSEV
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 1mg/mL BSA, 30% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2539896
Product Specific Information
IHC(P) analysis shows positive staining of GPR6 in human ileum mucosa and enteric ganglion tissue.
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR6 is an orphan, constitutively active G-coupled protein receptor, involved in a wide array of functions such as neurite growth, amyloid processing and appetitive learning. GPR6 is predominantly expressed in neurons in the striatum of the brain. GPR6 was found to be expressed on the cell surface and in intracellular compartments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor 6; RCNL3; Sphingosine 1-phosphate receptor GPR6
Gene Aliases: GPR6
UniProt ID: (Human) P46095
Entrez Gene ID: (Human) 2830
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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