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NeoBiotechnologies
GRAMD4 (Transcription Factor) Monoclonal Antibody (PCRP-GRAMD4-1A10)
Product Details
23151-MSM1-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
PCRP-GRAMD4-1A10
Immunogen
Recombinant full-length human GRAMD4 protein
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
Product Specific Information
Predicted to react in Rat
Target Information
GRAMD4 also termed as Death inducing protein is a 578 amino-acid protein, which contains 1 GRAM domain. GRAMD4 as a multi-pass membrane protein localizes in the Mitochondrion membrane. Overexpression of GRAMD4 results in a strong apoptotic response involving caspase-3 activation and cleavage of poly (ADP-ribose)-polymerase. GRAMD4 is expressed in lung and in primary lung squamous cell carcinoma (LSCC) and shows up-regulation in mitochondria by E2F-1 after addition of 4-hydroxytamoxifen. This evidence suggests that GRAMD4 may be a potential target for cancer therapies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Death-inducing protein; death-inducing-protein; GRAM domain-containing protein 4; GRAM domain-containing protein 4 (GRAMD4)
Gene Aliases: dA59H18.1; DIP; dJ439F8.1; GRAMD4; KIAA0767
UniProt ID: (Human) Q6IC98
Entrez Gene ID: (Human) 23151
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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