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Product Details
PA5-57131
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GRB14. Recombinant protein control fragment (Product #RP-102645).
Conjugate
Form
Liquid
Concentration
0.08 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642206
Product Specific Information
Immunogen sequence: PELCCSPFTS VLSADLFPKA NSRKKQVIKV YSEDETSRAL DVPSDITARD VCQLLILKNH YIDDHSWTLF EHLPHIGVER TIEDHELVIE
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 81%.
Target Information
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GRB14 adapter protein; Growth factor receptor-bound protein 14
Gene Aliases: GRB14
UniProt ID: (Human) Q14449
Entrez Gene ID: (Human) 2888
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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