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This antibody recognizes the N-terminal of GRB7.
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B47; Epidermal growth factor receptor GRB-7; GRB7 adapter protein; Growth factor receptor-bound protein 7; Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7); OTTHUMP00000164352
Gene Aliases: GRB7; mKIAA4028
UniProt ID: (Human) Q14451, (Mouse) Q03160
Entrez Gene ID: (Human) 2886, (Mouse) 14786
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