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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • GRB7 Antibodies

          Invitrogen

          GRB7 Recombinant Rabbit Monoclonal Antibody (23GB6445)

          View all (21) GRB7 antibodies
          Datasheet
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          Datasheet
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          Cite GRB7 Recombinant Rabbit Monoclonal Antibody (23GB6445)

          • Antibody Testing Data (2)
          GRB7 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          GRB7 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          GRB7 Antibody (MA5-53052) in WB

          Western Blot analysis of GRB7. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with GRB7 recombinant monoclonal antibody (Product # MA5-53052) with a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody with a dilution of 1:20,000. Image was developed using FeQTM ECL Substrate Kit. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GRB7 Antibody in Western Blot (WB)
          GRB7 Antibody in Flow Cytometry (Flow)

          Product Details

          MA5-53052

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:5,000
          -

          Flow Cytometry (Flow)

          1:2,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293F

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          23GB6445

          Immunogen

          A synthesized peptide derived from human GRB7 (1-100AA).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3249527

          Target Information

          The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: B47; Epidermal growth factor receptor GRB-7; GRB7 adapter protein; Growth factor receptor-bound protein 7; OTTHUMP00000164352

          View more View less

          Gene Aliases: GRB7

          View more View less

          UniProt ID: (Human) Q14451

          View more View less

          Entrez Gene ID: (Human) 2886

          View more View less

          Function(s)
          RNA binding SH3/SH2 adaptor activity protein binding protein kinase binding phosphatidylinositol binding identical protein binding
          Process(es)
          epidermal growth factor receptor signaling pathway positive regulation of signal transduction negative regulation of translation positive regulation of cell migration stress granule assembly ERBB2 signaling pathway leukocyte migration
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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