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This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure.
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Protein Aliases: centromere protein 35; GRC5; jumonji C domain-containing histone demethylase 1E; Lysine-specific demethylase PHF2; PHD finger protein 2
Gene Aliases: CENP-35; GRC5; JHDM1E; KIAA0662; PHF2
UniProt ID: (Human) O75151, (Mouse) Q9WTU0
Entrez Gene ID: (Human) 5253, (Mouse) 18676, (Rat) 306814
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