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Invitrogen
GRE2 Polyclonal Antibody
FIGURE: 1 / 1
GRE2 Antibody (PA5-144560) in WB
Western blot analysis of GRE2 in recombinant protein using a dilution of 1:1,000. Samples were incubated with GRE2 polyclonal antibody (Product # PA5-144560). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 30 kDa. Observed band size: 30 kDa.
Product Details
PA5-144560
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Yeast
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508/S288c) (Baker's yeast) GRE2 protein (1-120aa)
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3091713
Target Information
Catalyzes the irreversible reduction of the cytotoxic compound methylglyoxal (MG, 2-oxopropanal) to (S)-lactaldehyde as an alternative to detoxification of MG by glyoxalase I GLO1. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation. Also catalyzes the reduction of 3-methylbutanal to 3-methylbutanol. Acts as a suppressor of 3-methylbutanol-induced filamentation by modulating the levels of 3-methylbutanal, the signal to which cells respond by filamentation. Also involved in ergosterol metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-methylbutanal reductase; Genes de respuesta a estres protein 2; Isovaleraldehyde reductase; methylglyoxal reductase (NADPH-dependent) GRE2; NADPH-dependent methylglyoxal reductase; NADPH-dependent methylglyoxal reductase GRE2
Gene Aliases: GRE2; YOL151W
UniProt ID: (Baker's yeast) Q12068
Entrez Gene ID: (Baker's yeast) 854014
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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