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Invitrogen
GRHL2 Monoclonal Antibody (CL3760)
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FIGURE: 1 / 5
GRHL2 Antibody (MA5-31388) in ICC/IF
Immunofluorecent analysis of GRHL2 in A-431 cells using GRHL2 Monoclonal Antibody (CL3760) (Product # MA5-31388). Staining shows specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Product Details
MA5-31388
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CL3760
Immunogen
Recombinant protein corresponding to Human GRHL2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787024
Product Specific Information
Immunogen sequence: NRVQVLKTVP VNLSLNQDHL ENSKREQYSI SFPESSAIIP VSGITVVKAE DFTPVFMAPP VHYPRGDGEE QRVVIFEQTQ YDVPSLATHS AYLKDDQRST PDSTYSESFK DAATEKFRSA SVGAEEYMYD QTSSGTFQYT LEATKSLRQK
Target Information
The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brother of mammalian grainyhead; grainyhead-like 2; Grainyhead-like protein 2 homolog; grainyhead-like transcription factor 2; Transcription factor CP2-like 3
Gene Aliases: BOM; DFNA28; ECTDS; GRHL2; TFCP2L3
UniProt ID: (Human) Q6NT03
Entrez Gene ID: (Human) 79977
intronic transcription regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
chromatin DNA binding
sequence-specific DNA binding
neural tube closure
cardiac ventricle morphogenesis
epithelial cell morphogenesis
transcription from RNA polymerase II promoter
cell adhesion
brain development
cell proliferation
epidermis development
neural tube development
cell junction assembly
multicellular organism growth
embryonic digit morphogenesis
camera-type eye development
regulation of DNA methylation
negative regulation of keratinocyte differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic cranial skeleton morphogenesis
positive regulation of telomerase activity
face development
lung lobe morphogenesis
lung epithelial cell differentiation
epithelial cell morphogenesis involved in placental branching
bicellular tight junction assembly
epithelium migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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