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Immunogen sequence: VGYTPDVLT DTTAELAVSL LLTTCRRLPE AIEEVKNGGW TSWKPLWLCG YGLTQSTVGI IGLGRIGQAI ARRLKPFGVQ RFLYTGRQPR PEEAAEFQAE FVSTPELAAQ SDFIVVACSL TPATEGLCNK DFFQKMKETA VFINISRGDV VNQDDLYQAL ASGKIAAAGL DVTSPEPLPT NHPLLTLKNC VILPHIGSAT HRTRNTMSLL AANNLLAGLR GEPMPSELKL (100-328 aa encoded by BC000605)
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glycerate-2-dehydrogenase; Glyoxylate reductase/hydroxypyruvate reductase
Gene Aliases: 1110059D05Rik; 6430629L09Rik; GLXR; GLYD; GRHPR; MSTP035; PH2
UniProt ID: (Human) Q9UBQ7, (Mouse) Q91Z53
Entrez Gene ID: (Human) 9380, (Mouse) 76238
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