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Despite its predicted molecular weight, Grik4 often migrates at a lower molecular weight in SDS-PAGE. A suggested positive control is rat brain tissue lysate.
PA5-20453 can be used with blocking peptide PEP-0570.
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EAA1; Excitatory amino acid receptor 1; GluK4; glutamate receptor; Glutamate receptor ionotropic, kainate 4; Glutamate receptor KA-1; glutamate receptor KA1; glutamate receptor, ionotropic, kainate 4; KA1; kainate receceptor
Gene Aliases: 6330551K01Rik; EAA1; GluK4; GluRgamma1; GRIK; GRIK4; KA-1; KA1
UniProt ID: (Human) Q16099, (Rat) Q01812, (Mouse) Q8BMF5
Entrez Gene ID: (Human) 2900, (Rat) 24406, (Mouse) 110637
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