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FIGURE: 1 / 1
The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
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Protein Aliases: Glutamate [NMDA] receptor-associated protein 1; glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); glutamate receptor, NMDA subtype, glutamate-binding subunit; N-methyl-D-aspartate receptor glutamate-binding chain; NMDA receptor glutamate-binding chain; NMDA receptor glutamate-binding subunit; Protein lifeguard 1; Putative MAPK-activating protein PM02; transmembrane BAX inhibitor motif containing 3; Transmembrane BAX inhibitor motif-containing protein 3
Gene Aliases: 1110025J15Rik; GRINA; HNRGW; Lag; LFG1; NMDARA1; TMBIM3
UniProt ID: (Human) Q7Z429, (Mouse) Q9ESF4, (Rat) Q6P6R0
Entrez Gene ID: (Human) 2907, (Mouse) 66168, (Rat) 266668
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