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GRINA Antibody (PA5-116678) in WB
Western blot analysis of GRINA in extracts of mouse pancreas. Samples were incubated with GRINA Polyclonal antibody (Product # PA5-116678) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-116678
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GRINA (NP_0008281)
Conjugate
Form
Liquid
Concentration
0.59 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901309
Product Specific Information
Positive Samples: Mouse pancreas
Immunogen sequence: MSHEKSFLVS GDNYPPPNPG YPGGPQPPMP PYAQPPYPGA PYPQPPFQPS PYGQPGYPHG PSPYPQGGYP QGPYPQGGYP QGPYPQEGYP QGPYPQGGYP
Target Information
The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glutamate [NMDA] receptor-associated protein 1; glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); glutamate receptor, NMDA subtype, glutamate-binding subunit; N-methyl-D-aspartate receptor glutamate-binding chain; NMDA receptor glutamate-binding chain; NMDA receptor glutamate-binding subunit; Protein lifeguard 1; Putative MAPK-activating protein PM02; transmembrane BAX inhibitor motif containing 3; Transmembrane BAX inhibitor motif-containing protein 3
Gene Aliases: 1110025J15Rik; GRINA; HNRGW; Lag; LFG1; NMDARA1; TMBIM3
UniProt ID: (Human) Q7Z429, (Mouse) Q9ESF4, (Rat) Q6P6R0
Entrez Gene ID: (Human) 2907, (Mouse) 66168, (Rat) 266668
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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