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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CXCL1 (GRO alpha) Antibodies

          Proteintech

          GRO alpha Polyclonal Antibody

          45 References
          View all (31) CXCL1 (GRO alpha) antibodies

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          Cite GRO alpha Polyclonal Antibody

          • Antibody Testing Data (4)
          GRO alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          GRO alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 4

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          GRO alpha Antibody (12335-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using (Product # 12335-1-AP) (GRO alpha antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GRO alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GRO alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GRO alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GRO alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          12335-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          -
          View 13 publications 13 publications

          Immunohistochemistry (IHC)

          -
          View 19 publications 19 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          -
          View 12 publications 12 publications

          ELISA (ELISA)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          GRO alpha Fusion Protein Ag2917 (1-107 aa encoded by BC011976)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.21 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MARAALSAA PSNPRLLRVA LLLLLLVAAG RRAAGASVAT ELRCQCLQTL QGIHPKNIQS VNVKSPGPHC AQTEVIATLK NGRKACLNPA SPIVKKIIEK MLNSDKSN (1-107 aa encoded by BC011976)

          Target Information

          CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: alpha-chemokine; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 1; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); CXC; CXC motif chemokine; CXCL; CXCL-1; fibroblast secretory protein; GRO a; GRO α; GRO-alpha(1-73); GRO1 oncogene; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GROalpha; Growth-regulated alpha protein; GROα; KC/GR)-alpha; KC/GRO-alpha; melanoma growth stimulating activity, alpha; Melanoma growth stimulatory activity; melanoma growth stimulatory activity alpha; MGSA; MGSA alpha; NAP-3; NAP3; Neutrophil-activating protein 3; Platelet-derived growth factor-inducible protein KC; Secretory protein N51

          View more View less

          Gene Aliases: CXCL1; FSP; GRO; GRO1; GROA; KC; MGSA; MGSA-a; N51; NAP-3; SCYB1

          View more View less

          UniProt ID: (Human) P09341, (Mouse) P12850

          View more View less

          Entrez Gene ID: (Human) 2919, (Mouse) 14825

          View more View less

          Function(s)
          receptor binding chemokine activity enzyme activator activity growth factor activity CXCR chemokine receptor binding cytokine activity
          Process(es)
          chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor signaling pathway nervous system development cell proliferation negative regulation of cell proliferation actin cytoskeleton organization response to lipopolysaccharide intracellular signal transduction positive regulation of catalytic activity cell chemotaxis chemokine-mediated signaling pathway positive regulation of neutrophil chemotaxis response to molecule of bacterial origin acute inflammatory response positive regulation of leukocyte chemotaxis positive regulation of cytosolic calcium ion concentration positive regulation of sodium ion transport neutrophil chemotaxis positive regulation of superoxide anion generation positive regulation of potassium ion transport positive regulation of neutrophil mediated killing of fungus positive regulation of hematopoietic stem cell proliferation
          It has to be done as per old AB suggested Products section.
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