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Proteintech
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Immunogen sequence: MAVRSLWAG RLRVQRLLAW SAAWESKGWP LPFSTATQRT AGEDCRSEDP PDELGPPLAE RALRVKAVKL EKEVQDLTVR YQRAIADCEN IRRRTQRCVE DAKIFGIQSF CKDLVEVADI LEKTTECISE ESEPEDQKLT LEKVFRGLLL LEAKLKSVFA KHGLEKLTPI GDKYDPHEHE LICHVPAGVG VQPGTVALVR QDGYKLHGRT IRLARVEVAV ESQRRL (1-225 aa encoded by B C070090)
GRPEL2 (GrpE Like 2, Mitochondrial) is a Protein Coding gene. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL1. Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: actin filament-associated protein 1-like 1; AFAP1-like protein 1; GrpE protein homolog 2, mitochondrial; GrpE-like 2, mitochondrial; Mt-GrpE#2
Gene Aliases: Afap1l1; GRPEL2; Mt-GrpE#2; Mt-grpel2
UniProt ID: (Human) Q8TAA5, (Mouse) O88396
Entrez Gene ID: (Human) 134266, (Mouse) 17714, (Rat) 688777
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