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Product Details
H00134266-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GRPEL2 (NP_689620.2, 1 a.a. approximately 225 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAVRSLWAGR LRVQRLLAWS AAWESKGWPL PFSTATQRTA GEDCRSEDPP DELGPPLAER ALRVKAVKLE KEVQDLTVRY QRAIADCENI RRRTQRCVED AKIFGIQSFC KDLVEVADIL EKTTECISEE SEPEDQKLTL EKVFRGLLLL EAKLKSVFAK HGLEKLTPIG DKYDPHEHEL ICHVPAGVGV QPGTVALVRQ DGYKLHGRTI RLARVEVAVE SQRRL
Target Information
GRPEL2 (GrpE Like 2, Mitochondrial) is a Protein Coding gene. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL1. Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GrpE protein homolog 2, mitochondrial; GrpE-like 2, mitochondrial; Mt-GrpE#2
Gene Aliases: GRPEL2; Mt-GrpE#2
UniProt ID: (Human) Q8TAA5
Entrez Gene ID: (Human) 134266
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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