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Positive Samples: HeLa, mouse kidney
Immunogen sequence: SLLPQSLAAA AAVPTRSYSQ ESKTTYLEDL PPPPEYELAP SKLEEEVDDV FLIRAQGLPW SCTMEDVLNF FSDCRIRNGE NGIHFLLNRD GKRRGDALIE M
G-rich sequence factor 1 (GRSF1) is a regulator of post-transcriptional mitochondrial gene expression. It required for assembly of the mitochondrial ribosome and for recruitment of mRNS and IncRNA. GRSF1 binds RNAs containing the 14 base G-rich element. It preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-NDS - each of which contains multiple consensus binding sequences.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G-rich sequence factor 1; GRSF-1
Gene Aliases: BB232551; C80280; D5Wsu31e; GRSF1
UniProt ID: (Human) Q12849, (Mouse) Q8C5Q4
Entrez Gene ID: (Human) 2926, (Mouse) 231413, (Rat) 305256
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